Artist:
Florence and The Machine
Track:
Howl
Plays:
252,509 plays

(Source: thesimgrove)

captioningcrusader:

anyone who’s been following this blog knows that we’re highly susceptible to popular memes  

st0rmur:

Why was this show ever cancelled. It was gold.

(Source: teflonly)

dr-shemp:

drjamesmccrimmon:

Reasons why the Highlanders should be found: Doctor in a dress

doctor in a dress

lets all answer his s.o.s

wildunicornherd:

thinksquad:

Here is a Science fair project presented by a girl in a secondary school in Sussex . In it she took filtered water and divided it into two parts. The first part she heated to boiling in a pan on the stove, and the second part she heated to boiling in a microwave. Then after cooling she used the water to water two identical plants to see if there would be any difference in the growth between the normal boiled water and the water boiled in a microwave. She was thinking that the structure or energy of the water may be compromised by microwave. As it turned out, even she was amazed at the difference, after the experiment which was repeated by her class mates a number of times and had the same result.

It has been known for some years that the problem with microwaved anything is not the radiation people used to worry about, it’s how it corrupts the DNA in the food so the body can not recognize it.

Microwaves don’t work different ways on different substances. Whatever you put into the microwave suffers the same destructive process. Microwaves agitate the molecules to move faster and faster. This movement causes friction which denatures the original make-up of the substance. It results in destroyed vitamins, minerals, proteins and generates the new stuff called radiolytic compounds, things that are not found in nature.

So the body wraps it in fat cells to protect itself from the dead food or it eliminates it fast. Think of all the Mothers heating up milk in these ‘Safe’ appliances. What about the nurse in Canada that warmed up blood for a transfusion patient and accidentally killed him when the blood went in dead. But the makers say it’s safe. But proof is in the pictures of living plants dying!

NO, YOU PIG-IGNORANT ASSWIPES.

SOME KID’S CLASS PROJECT IS NOT REAL SCIENTIFIC RESEARCH. YOU’VE HEARD OF “DOUBLE BLIND”, RIGHT? CALL ME WHEN IT’S PUBLISHED IN NATURE.

the structure or energy of the water

what the fuck does that even mean you realize that a water molecule is made up of three fucking atoms and if you rearrange it it isn’t water anymore and you would fucking notice

the problem with microwaved anything is not the radiation people used to worry about

Here is a handy diagram I drew of all the different types of radiation:

The Electromagnetic Spectrum Cheat Sheet

Microwaves != nuclear reactors, so calm your tits.

it’s how it corrupts the DNA in the food so the body can not recognize it

…do you understand what DNA is and how eating works? DNA is a jumble of protein nucleic acid in the middle of each cell and it tells the cells in that particular organism how to make more cells. Your body does not care about whether your food has any DNA in it or not. The chemicals it cares about are things like vitamins and sugars, as well as inorganic shit like salt.

(You can denature DNA by heating it or using chemicals like urea. It is like what happens when you fry an egg, which is basically a big glob of protein—the strands break apart and it looks like tiny white strings. Very cool.)

Microwaves agitate the molecules to move faster and faster.

I…just…that is the fucking definition of heat, whether you’re heating something over a flame or in a microwave or using the Sun. The difference is that microwaves mostly affect the water molecules in your food and they don’t need to use as much heat. Water boils at 100°C, which is just about as hot as water can get before it just turns into steam; but that’s like the lowest setting on your oven. Oven- or stove-cooked food tastes different partly because it uses higher temperatures and partly because heat is transferred in a different way.

This movement causes friction

That’s not what friction is.

It results in destroyed vitamins, minerals, proteins and generates the new stuff called radiolytic compounds, things that are not found in nature.

Let’s take these one at a time.

  • Vitamins are classified as water-soluble or fat-soluble. So cooking things in water will dissolve the water-soluble vitamins (C and all the B’s). Just plain heat doesn’t do that, so microwaving veggies—which keeps the water in—is actually a healthier option.
  • Proteins: Breaking the chemical bonds in proteins (denaturing) is a part of any cooking. However, denatured protein is still nutritious—that’s why you can meet your protein intake with foods like fried eggs and baked chicken.
  • Minerals are just chemical elements, like off the periodic table—sodium, iron, potassium. (Vitamins and proteins are very complex combinations of elements.)

Which brings me to the “radiolytic compound” bullshit. When you talk about breaking apart, say, iron—you’re talking about breaking down the iron atoms themselves. Which is a whole lot different than breaking the bonds between atoms. It takes hella radiation. You need shit like gamma rays—the OOOH SCARY NUCULAR radiation—which we’ve already established do not come from your microwave.

things that are not found in nature

What the shit does that even mean? You all know radioactive elements occur in nature, right? In rocks and also in living cells. That’s right, you have this radioactive kind of carbon INSIDE YOU. You get it by eating those delicious plants. We can tell how long ago something died by how much of it is left.

Tons of shit that occurs naturally is horribly bad for you. And tons of shit that never existed until we cooked it up is great for you—like the chemical compounds in a lot of medications.

PEOPLE WHO BELIEVE THIS SHIT ARE WHY CHILDHOOD DISEASES THAT CAUSED SERIOUS ILLNESSES AND/OR DEATH THAT WE NEARLY ERADICATED WITH VACCINES ARE NOW COMING BACK AND WHY CONSPIRACY THEORIST TWATS ARE ASKING CITY COUNCIL NOT TO FLUORIDATE THE WATER AND WHY GLOBAL WARMING WILL WRECK OUR FUCKING PLANET.

LERN 2 SCIENCE. Think before you reblog. And microwave your veggies.

(Source: thinksquad)

Sylvester McCoy outtakes.

» Establishing a Dax Timeline: An Attempt

letstalkabouttrek:

Note: because non-canon sources such as The Lives of Dax provide information that directly contradict show canon in many places, this will be derived mostly from information given in the show.

The Dax symbiont wss born in 2018.

Presumably, the symbiont then spent a long amount of time growing in the Breeding Pools.

Lela Dax, the first host, was joined in 2168 at the age of 56. The symbiont is now 150.

Lela was a legislator, and one of the first women ever appointed to the Triil Council. She had at lest one child, a son named Ahjess.

Lela died at the age of 114 in 2226 and Dax was joined to Tobin Dax. The symbiont is now 208. 

Tobin was an engineer. He was also a vegetarian, never got drunk, bit his nails, and tried his hand at magic tricks and botany. At some point he met the exiled Cardassian poet Iloja. He had at least one child, named Raifi. 

It is unknown when Tobin died and the symbiont was joined to Emony Dax.  However, Emony met Leonard McCoy while he was in college, placing their interaction likely in the mid-2240’s (McCoy would have been 18 in 2245). Therefore it is probable that Emony was joined some time in the early 2240’s.

Emony was a gymnast and stood on her head to relax, but little is known about other aspects of her life. However, Jadzia’s statement that Dax had been a mother three times, combined with the fact that there were only 3 female hosts before her, implies that she had at least one child.

It is unknown when Emony died and the symbiont was joined to Audrid Dax. However, taking biological information of Audred into account, it is likely that this happened in the early 2260’s at the absolute latest.

Audrid became the head of the Trill Symbiosis Commission. She had at least two children, Neema and Gran.

Audrid died in 2284 and Dax was joined with Torias Dax. The symbiont is now 266.

Torias was a pilot. He had extensive combat experience. He was married to Nilani Kahn, but no children were ever mentioned. 

Torias was killed in a shuttle crash in 2285 and the symbiont was passed to Joran Dax

Joran was a musician. He became unstable following his joining killed at least 3 people.  He had a brother named Yolad.

The Dax symbiont was removed from Joran, given a memory block, and joined to Curzon Dax later in 2285. The symbiont is now 267.

Cuzon was an acclaimed ambassador. He had a great understanding of and respect for Klingon culture, and therefore represented The Federation at the Khitomir Accords in 2293. He had a reputation as a womanizer. He served as a mentor to Benjamin Sisko starting in the early or mid-2350’s. As a field docent, he “broke” several Initiates. 

It was never stated that Curzon Dax had any children. However, according to Jadzia, the Dax symbiont had been a father twice. Because it is established that Tobin Dax had children, either Curzon or Torias must have been the other father (at the time of Jadzia’s statement the memory block on Joran was still in effect). Given Torias’s short life and Curzon’s reputation, Curzon is the more likely candidate. He was most likely not married, however, since Jadzia later said that Dax had been a groom twice - Torias was known to be married, and it’s likely that Tobin was as well.

Curzon died in 2367 and Dax was joined with Jadzia Dax. The symbiont is now 349. 

Jadzia served as the science officer aboard Deep Space Nine, where she was reunited with Sisko. She dated several individuals before beginning a relationship with Worf, who she would marry. She fought at the front lines of the Dominion War in the early 2370’s.

Jadzia was killed in 2374, and during transport Dax had to be suddenly joined with Ezri Dax. The symbiont is now 356.

Ezri had been serving as a counselor aboard the USS Destiny, but after once again meeting Benjamin Sisko she transferred to DS9. In 2375 she entered into a relationship with Julian Bashir.

The Dax symbiont was last seen in canon in 2375, at which time it was aged 357. 

(Source: hedwwig)

itistimetodisappear:

"That’s your mother!?”

crankybucky:

Sam Wilson has a bunch of qualities i love in superheroes and characters in general because

  • he is a well-drawn character - his backstory isn’t really outlandish or anything, he’s a veteran who lost his buddy, that’s a pretty relatable story to anyone who’s ever lost anyone EVER
  • right from the very first moment we see him he has a great sense of humour and he’s pretty much always smiling - but he doesn’t take that humour too far, he knows when to joke and try and make Steve feel better, and he knows when he be serious, which is an important skill
  • he’s ESSENTIAL and really helpful, literally if it wasn’t for Sam Wilson one of the helicarriers would have killed a bunch of people - additionally, he’s selfless, and he didn’t think twice about endangering himself for the mission (during which he was an A+ team player, another great quality in a superhero)
  • he’s extremely moral - when Captain America needs his help, he steps up and helps, regardless of the fact that he could get in trouble - because it’s the right thing to do
  • DID I ALREADY MENTION HE’S SELFLESS well i’m gonna go ahead and double-tick that box because when Steve wakes up after nearly drowning, guess who’s at his bedside - yup, Sam Wilson, waiting patiently at his bedside with the Troubleman sountrack playing quietly in the background (just in case Steve didn’t get the chance to listen to it yet)
  • also, good taste in music
  • his ‘the kind you stop’ speech is both sensible and sensitive - rather than just leave it to Steve to work through his issues regarding fighting Bucky on his own, Sam offers him support, and guidance - sure, he tells him he needs to stop Bucky, but he doesn’t do it in such a way that doesn’t give Steve a choice. He’s not telling Steve to definitely kill Bucky - that’s not the kind of guy he is, he know that’s not really right. And besides - he empathises with Steve, about losing a buddy in the line of duty
  • WHICH BRINGS ME ONTO HIS COUNSELLING SKILLS i’m really glad that the movie established that veterans require therapy and have things to work through after combat, because often therapy is brushed over when films deal with PTSD sufferers, despite it being really important in the vast majority of cases. Sam is both recovering, and helping others recover - just another testament to his good character imo
  • plus counselling isn’t easy, but he makes it look effortless, and in no way awkward
  • he’s good, and supportive, but without being preachy or overbearing 
  • HIS WINGS ARE FUCKING AWESOME OKAY. He can fly
  • He’s the only person to ask what Steve wants, and to make him stop and consider that (aside from Peggy, during the war)
  • All of my praise for Sam Wilson
  • unleash the Falcon
  • we need more of him
  • desperately

(Source: bucksterbarnes)

(Source: cabbagefuneral)

(Source: littleborgqueen)

vinegod:

Every time I write an essay… by Thomas Sanders

neurosciencestuff:

(Image caption: In a study of brains from children with autism, neurons in brains from autistic patients did not undergo normal pruning during childhood and adolescence. The images show representative neurons from unaffected brains (left) and brains from autistic patients (right); the spines on the neurons indicate the location of synapses. Credit: Guomei Tang, PhD and Mark S. Sonders, PhD/Columbia University Medical Center)

Children with Autism Have Extra Synapses in Brain

Children and adolescents with autism have a surplus of synapses in the brain, and this excess is due to a slowdown in a normal brain “pruning” process during development, according to a study by neuroscientists at Columbia University Medical Center (CUMC). Because synapses are the points where neurons connect and communicate with each other, the excessive synapses may have profound effects on how the brain functions. The study was published in the August 21 online issue of the journal Neuron.

A drug that restores normal synaptic pruning can improve autistic-like behaviors in mice, the researchers found, even when the drug is given after the behaviors have appeared.

“This is an important finding that could lead to a novel and much-needed therapeutic strategy for autism,” said Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUMC and director of New York State Psychiatric Institute, who was not involved in the study.

Although the drug, rapamycin, has side effects that may preclude its use in people with autism, “the fact that we can see changes in behavior suggests that autism may still be treatable after a child is diagnosed, if we can find a better drug,” said the study’s senior investigator, David Sulzer, PhD, professor of neurobiology in the Departments of Psychiatry, Neurology, and Pharmacology at CUMC.

During normal brain development, a burst of synapse formation occurs in infancy, particularly in the cortex, a region involved in autistic behaviors; pruning eliminates about half of these cortical synapses by late adolescence. Synapses are known to be affected by many genes linked to autism, and some researchers have hypothesized that people with autism may have more synapses.

To test this hypothesis, co-author Guomei Tang, PhD, assistant professor of neurology at CUMC, examined brains from children with autism who had died from other causes. Thirteen brains came from children ages two to 9, and thirteen brains came from children ages 13 to 20. Twenty-two brains from children without autism were also examined for comparison.

Dr. Tang measured synapse density in a small section of tissue in each brain by counting the number of tiny spines that branch from these cortical neurons; each spine connects with another neuron via a synapse.

By late childhood, she found, spine density had dropped by about half in the control brains, but by only 16 percent in the brains from autism patients.

“It’s the first time that anyone has looked for, and seen, a lack of pruning during development of children with autism,” Dr. Sulzer said, “although lower numbers of synapses in some brain areas have been detected in brains from older patients and in mice with autistic-like behaviors.”

Clues to what caused the pruning defect were also found in the patients’ brains; the autistic children’s brain cells were filled with old and damaged parts and were very deficient in a degradation pathway known as “autophagy.” Cells use autophagy (a term from the Greek for self-eating) to degrade their own components.

Using mouse models of autism, the researchers traced the pruning defect to a protein called mTOR. When mTOR is overactive, they found, brain cells lose much of their “self-eating” ability. And without this ability, the brains of the mice were pruned poorly and contained excess synapses. “While people usually think of learning as requiring formation of new synapses, “Dr. Sulzer says, “the removal of inappropriate synapses may be just as important.”

The researchers could restore normal autophagy and synaptic pruning—and reverse autistic-like behaviors in the mice—by administering rapamycin, a drug that inhibits mTOR. The drug was effective even when administered to the mice after they developed the behaviors, suggesting that such an approach may be used to treat patients even after the disorder has been diagnosed.

Because large amounts of overactive mTOR were also found in almost all of the brains of the autism patients, the same processes may occur in children with autism.

“What’s remarkable about the findings,” said Dr. Sulzer, “is that hundreds of genes have been linked to autism, but almost all of our human subjects had overactive mTOR and decreased autophagy, and all appear to have a lack of normal synaptic pruning. This says that many, perhaps the majority, of genes may converge onto this mTOR/autophagy pathway, the same way that many tributaries all lead into the Mississippi River. Overactive mTOR and reduced autophagy, by blocking normal synaptic pruning that may underlie learning appropriate behavior, may be a unifying feature of autism.”

Alan Packer, PhD, senior scientist at the Simons Foundation, which funded the research, said the study is an important step forward in understanding what’s happening in the brains of people with autism.

“The current view is that autism is heterogeneous, with potentially hundreds of genes that can contribute. That’s a very wide spectrum, so the goal now is to understand how those hundreds of genes cluster together into a smaller number of pathways; that will give us better clues to potential treatments,” he said.

“The mTOR pathway certainly looks like one of these pathways. It is possible that screening for mTOR and autophagic activity will provide a means to diagnose some features of autism, and normalizing these pathways might help to treat synaptic dysfunction and treat the disease.”

"I look around and you know what I see? Losers.
        But life’s giving us a chance.”

# WHAT A BUNCH OF AHOLES# WHO SAVE THE WORLD WITH FRIENDSHIP

(Source: peterquill)